Connecting Neurons...

August 3:

Vincent Pieribone

Duncan Hall 11 am

Genetically Encoded Voltage Indicators

Genetically encoded indicators of voltage offer the promise of less invasive monitoring of identified neuronal activity. Several fluorescent indicators have been developed but the use in in vivo experiments remains minimal. I will discuss efforts by our laboratory to produce indicators that perform better in in vivo experiments in mammalian cortex. This involves novel fluorescent protein discovery and engineering of indicator molecules as well as in vivo application in mammalian brain.

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